Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced expression of the osteoblastic phenotype on substrates that modulate fibronectin conformation and integrin receptor binding.

Biomaterials - 1 Jun 2002

Stephansson Sean N, Byers Benjamin A, García Andrés J

Abstract excerpt

Integrins represent the primary mechanism of cell-extracellular matrix interactions and control cell morphology, proliferation, and differentiation. We have previously shown that substrate-dependent modulation of adsorbed fibronectin (Fn) conformation alters alpha5beta1 integrin binding to Fn and directs C2C12 myoblast proliferation and differentiation (Mol. Biol. Cell 10 (1999) 785). The model substrates used in...

Topics

Alkaline Phosphatase
Animals
Antibodies
Calcification, Physiologic
Cattle
Cell Line
Fibronectins
Focal Adhesions
Humans
Integrin alpha5beta1
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Osteoblasts

Phenotype

Polymerase Chain Reaction

Protein Binding

Protein Structure, Tertiary

Source

Identifiers

PMID: 12033600
DOI: 10.1016/s0142-9612(01)00387-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced expression of the osteoblastic phenotype on substrates that modulate fibronectin conformation and integrin receptor binding.PMID 12033600Read ↗

Phenotype and gene expression pattern of osteoblast-like cells cultured on polystyrene and hydroxyapatite with pre-adsorbed type-I collagen.Semantic proximity Read ↗

Interplay between integrins and cadherins to control bone differentiation upon BMP-2 stimulationSemantic proximity Read ↗

Correlating cell architecture with osteogenesis: first steps towards live single cell monitoringSemantic proximity Read ↗

Integrin Expression and Function on Human Osteoblast-like CellsSemantic proximity Read ↗

Restricted and coordinated expression of β3-integrin and bone sialoprotein during cultured osteoblast differentiationSemantic proximity Read ↗

Mechanically Strained Cells of the Osteoblast Lineage Organize Their Extracellular Matrix Through Unique Sites of αVβ3-Integrin ExpressionSemantic proximity Read ↗

Role of material surfaces in regulating bone and cartilage cell response.Semantic proximity Read ↗

Patterns of integrin expression in a human mandibular explant model of osteoblast differentiation.Semantic proximity Read ↗

Bone sialoprotein (BSP) is a crucial factor for the expression of osteoblastic phenotypes of bone marrow cells cultured on type I collagen matrix.Semantic proximity Read ↗

Nano hydroxyapatite-blasted titanium surface creates a biointerface able to govern Src-dependent osteoblast metabolism as prerequisite to ECM remodeling.Semantic proximity Read ↗

A Dominant Negative Cadherin Inhibits Osteoblast DifferentiationSemantic proximity Read ↗

Titanium substrata composition influences osteoblastic phenotype:In vitro studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.