Article
CSF biomarker profiles do not differentiate between the cerebellar and parkinsonian phenotypes of multiple system atrophy.
Parkinsonism & related disorders - 1 Dec 2007
Abdo W F, van de Warrenburg B P C, Kremer H P H, Bloem B R, Verbeek M M
Abstract excerpt
BACKGROUND: Multiple system atrophy (MSA) can clinically be divided into the cerebellar (MSA-C) and the parkinsonian (MSA-P) variants. It is unknown whether the variation in clinical expression is also reflected by a different underlying neurochemical profile. METHODS: We analyzed brain specific proteins and neurotransmitter metabolites in cerebrospinal fluid (CSF) of 26 patients with MSA-C and 19 with MSA-P....
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