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Donor Cell Lines Considerably Affect the Outcome of Somatic Nuclear Transfer in the Case of Bovines

1 Jan 2007

Abstract excerpt

Since the first successful nuclear transfer (NT) experiments were carried out, various somatic cell types have been used as donor cells for production of cloned animals. In most experiments, fibroblasts are used since they only need to be isolated and cultivated. Recently, some researchers have shown that different cell cultures from different sources possess different capacities to support preimplantation...

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PMID: 17446659
DOI: 10.1262/jrd.18177

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