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Article

Multicopy blaOXA-58 gene as a source of high-level resistance to carbapenems in Acinetobacter baumannii.

Antimicrobial agents and chemotherapy - 1 Jul 2007

Bertini Alessia, Poirel Laurent, Bernabeu Sandrine, Fortini Daniela, Villa Laura, Nordmann Patrice, Carattoli Alessandra

Abstract excerpt

The mechanisms at the origin of heterogeneous carbapenem resistance levels observed among Acinetobacter baumannii isolates collected in 2005 in a large University Hospital of Rome, Italy, were investigated. These isolates were related and possessed similar plasmids carrying the carbapenem-hydrolyzing oxacillinase gene bla(OXA-58) but showed variable levels of resistance to carbapenems. Analysis of sequences...

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Identifiers

PMID: 17438042
DOI: 10.1128/AAC.01502-06
PMCID: PMC1913244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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