Article
Human NADH:ubiquinone oxidoreductase deficiency: radical changes in mitochondrial morphology?
American journal of physiology. Cell physiology - 1 Jul 2007
Koopman Werner J H, Verkaart Sjoerd, Visch Henk Jan, van Emst-de Vries Sjenet, Nijtmans Leo G J, Smeitink Jan A M, Willems Peter H G M
Abstract excerpt
Malfunction of NADH:ubiquinone oxidoreductase or complex I (CI), the first and largest complex of the mitochondrial oxidative phosphorylation system, has been implicated in a wide variety of human disorders. To demonstrate a quantitative relationship between CI amount and activity and mitochondri...
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