Article
Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity.
Breast cancer research : BCR - 1 Jan 2007
Vincent-Salomon Anne, Gruel Nadège, Lucchesi Carlo, MacGrogan Gaëtan, Dendale Remi, Sigal-Zafrani Brigitte, Longy Michel, Raynal Virginie, Pierron Gaëlle, de Mascarel Isabelle, Taris Corinne, Stoppa-Lyonnet Dominique, Pierga Jean-Yves, Salmon Rémy, Sastre-Garau Xavier, Fourquet Alain, Delattre Olivier, de Cremoux Patricia, Aurias Alain
Abstract excerpt
INTRODUCTION: Typical medullary breast carcinoma (MBC) has recently been recognized to be part of the basal-like carcinoma spectrum, a feature in agreement with the high rate of TP53 mutations previously reported in MBCs. The present study was therefore designed to identify phenotypic and genetic alterations that distinguish MBCs from basal-like carcinomas (BLC). METHODS: Expression levels of estrogen receptor...
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