Article
Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs.
BMC genetics - 3 Apr 2007
Uhl George R, Liu Qing-Rong, Drgon Tomas, Johnson Catherine, Walther Donna, Rose Jed E
Abstract excerpt
BACKGROUND: Classical genetic studies indicate that nicotine dependence is a substantially heritable complex disorder. Genetic vulnerabilities to nicotine dependence largely overlap with genetic vulnerabilities to dependence on other addictive substances. Successful abstinence from nicotine displays substantial heritable components as well. Some of the heritability for the ability to quit smoking appears to...
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