Article
Recurrent spontaneous abortion and skewed X-inactivation: is there an association?
American journal of obstetrics and gynecology - 1 Apr 2007
Hogge W Allen, Prosen Tracy L, Lanasa Mark C, Huber Heather A, Reeves Matthew F
Abstract excerpt
OBJECTIVE: The purpose of this study was to determine whether there is an association between skewed X-inactivation and recurrent spontaneous abortion in a large, well-defined sample of women with recurrent loss. STUDY DESIGN: X-chromosome inactivation patterns were compared in 5 groups of women. Group 1 (recurrent spontaneous abortion) consisted of 357 women with 2 or more spontaneous losses. In group 2...
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