Article
Skewed X inactivation and recurrent spontaneous abortion.
Seminars in reproductive medicine - 1 Jun 2001
Robinson W P, Beever C, Brown C J, Stephenson M D
Abstract excerpt
Recent studies show that women experiencing recurrent spontaneous abortion exhibit nonrandom X-chromosome inactivation (XCI) more often than in controls. This suggests that genetic factors may be important in explaining the losses in this subset of women. Nonetheless there are a number of possible explanations for this finding and the underlying causes may be heterogeneous. One hypothesis commonly cited is that a...
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