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Shiga Toxin Gene Loss and Transfer In Vitro and In Vivo during Enterohemorrhagic <i>Escherichia coli</i> O26 Infection in Humans

31 Mar 2007

Abstract excerpt

Escherichia coli serogroup O26 consists of enterohemorrhagic E. coli (EHEC) and atypical enteropathogenic E. coli (aEPEC). The former produces Shiga toxins (Stx), major determinants of EHEC pathogenicity, encoded by bacteriophages; the latter is Stx negative. We have isolated EHEC O26 from patient stools early in illness and aEPEC O26 from stools later in illness, and vice versa. Intrapatient EHEC and aEPEC...

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PMID: 17400784
DOI: 10.1128/aem.02937-06

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