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Phage-mediated Shiga toxin (Stx) horizontal gene transfer and expression in non-Shiga toxigenic<i>Enterobacter</i>and<i>Escherichia coli</i>strains

23 Apr 2016

Abstract excerpt

Enterobacter cloacae M12X01451 strain recently identified from a clinical specimen produces a new Stx1 subtype (Stx1e) that was not neutralized by existing anti-Stx1 monoclonal antibodies. Acquisition of stx by Ent. cloacae is rare and origin/stability of stx1e in M12X01451 is not known. In this study, we confirmed the ability of Stx1a- and Stx1e-converting phages from an Escherichia coli O157:H7 strain RM8530...

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PMID: 27109772
DOI: 10.1093/femspd/ftw037

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