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Enterohemorrhagic Escherichia coli in human infection: in vivo evolution of a bacterial pathogen.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Sept 2005

Mellmann Alexander, Bielaszewska Martina, Zimmerhackl Lothar B, Prager Rita, Harmsen Dag, Tschäpe Helmut, Karch Helge

Abstract excerpt

BACKGROUND: Enterohemorrhagic Escherichia coli (EHEC) cause most cases of the hemolytic uremic syndrome (HUS) worldwide. To investigate genetic changes in EHEC during the course of human infection, we analyzed consecutive stool samples and shed isolates from patients with HUS, focusing on the genes encoding Shiga toxin (stx) and intimin (eae). METHODS: Sequential stool samples from 210 patients with HUS were...

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PMID: 16107974
DOI: 10.1086/432722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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