[Preliminary linkage analysis and mapping of keloid susceptibility locus in a Chinese pedigree].

Abstract excerpt

OBJECTIVE: To investigate the linkage between the susceptibility locus to keloid and two loci, 15q22.31-q23 and 18q21.1, the authors performed linkage analysis of a pedigree. METHODS: A five-generation Han Chinese family of keloid was investigated and confirmed. Venous blood samples of 32 members in this family were collected for PCR and genetic analysis. Seven microsatellite markers spanning the critical regions...

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