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Article

Complex regulation and multiple developmental functions of misfire, the Drosophila melanogaster ferlin gene.

BMC developmental biology - 26 Mar 2007

Smith Michelle K, Wakimoto Barbara T

Abstract excerpt

BACKGROUND: Ferlins are membrane proteins with multiple C2 domains and proposed functions in Ca2+ mediated membrane-membrane interactions in animals. Caenorhabditis elegans has two ferlin genes, one of which is required for sperm function. Mammals have several ferlin genes and mutations in the human dysferlin (DYSF) and otoferlin (OTOF) genes result in muscular dystrophy and hearing loss, respectively. Drosophila...

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Share to Fertilization
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17386097
DOI: 10.1186/1471-213X-7-21
PMCID: PMC1853072

Genes

DYSF
OTOF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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