Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Current use of pharmacogenetic testing: a national survey of thiopurine methyltransferase testing prior to azathioprine prescription.

Journal of clinical pharmacy and therapeutics - 1 Apr 2007

Fargher E A, Tricker K, Newman W, Elliott R, Roberts S A, Shaffer J L, Bruce I, Payne K

Abstract excerpt

BACKGROUND: Azathioprine is an immunosuppressant prescribed for the treatment of inflammatory conditions and after organ transplantation. Risk of neutropaenia has limited the effective use of azathioprine (AZA) and driven requirements for careful monitoring and blood tests. Thiopurine methyltransferase (TPMT) is a genetically moderated key enzyme involved in the metabolism of AZA that can be used to stratify...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Attitude of Health Personnel
Share to Azathioprine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Monitoring

Share to England

Share to Health Knowledge, Attitudes, Practice

Share to Methyltransferases

Share to Practice Guidelines as Topic

Share to Practice Patterns, Physicians'

Source

Identifiers

PMID: 17381669
DOI: 10.1111/j.1365-2710.2007.00805.x

Genes

TPMT
NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Current use of pharmacogenetic testing: a national survey of thiopurine methyltransferase testing prior to azathioprine prescription.PMID 17381669Read ↗

Implementation of TPMT testing.Semantic proximity Read ↗

Improving pharmacovigilance in Europe: TPMT genotyping and phenotyping in the UK and Spain.Semantic proximity Read ↗

Systematic review of thiopurine methyltransferase genotype and enzymatic testing strategies.Semantic proximity Read ↗

An audit of thiopurine methyltransferase genotyping and phenotyping before intended azathioprine treatment for dermatological conditions.Semantic proximity Read ↗

Thiopurine S-methyltransferase (TPMT) assessment prior to starting thiopurine drug treatment; a pharmacogenomic test whose time has come.Semantic proximity Read ↗

The cost-effectiveness of a pharmacogenetic test: a trial-based evaluation of TPMT genotyping for azathioprine.Semantic proximity Read ↗

Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy?Semantic proximity Read ↗

Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing.Semantic proximity Read ↗

Use of thiopurine testing in the management of inflammatory bowel diseases in clinical practice: a worldwide survey of experts.Semantic proximity Read ↗

A pharmacogenetic basis for the safe and effective use of azathioprine and other thiopurine drugs in dermatologic patients.Semantic proximity Read ↗

Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice.Semantic proximity Read ↗

Pharmacogenetic testing for drug metabolizing enzymes: is it happening in practice?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.