Article
Altered brain-derived neurotrophic factor blood levels and gene variability are associated with anorexia and bulimia.
Genes, brain, and behavior - 1 Nov 2007
Mercader J M, Ribasés M, Gratacòs M, González J R, Bayés M, de Cid R, Badía A, Fernández-Aranda F, Estivill X
Abstract excerpt
Murine models and association studies in eating disorder (ED) patients have shown a role for the brain-derived neurotrophic factor (BDNF) in eating behavior. Some studies have shown association of BDNF -270C/T single-nucleotide polymorphism (SNP) with bulimia nervosa (BN), while BDNF Val66Met variant has been shown to be associated with both BN and anorexia nervosa (AN). To further test the role of this...
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