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Article

The 196G/A (val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorder.

Neuroscience letters - 2 Oct 2006

Monteleone Palmiero, Zanardini Roberta, Tortorella Alfonso, Gennarelli Massimo, Castaldo Eloisa, Canestrelli Benedetta, Maj Mario

Abstract excerpt

The brain-derived neurotrophic factor (BDNF) is involved not only in promoting neuronal outgrowth and differentiation, synaptic connectivity and neuronal repair, but also in modulating eating behavior. Since genetic factors likely contribute to the biological vulnerability to bulimia nervosa (BN)...

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Source

Identifiers

PMID: 16901635
DOI: 10.1016/j.neulet.2006.07.040

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16901635-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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The 196G/A (val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorder.PMID 16901635Read ↗

Association between the brain-derived neurotrophic factor 196G/A polymorphism and eating disorders.Semantic proximity Read ↗

Altered brain-derived neurotrophic factor blood levels and gene variability are associated with anorexia and bulimia.Semantic proximity Read ↗

BDNF genetic variability modulates psychopathological symptoms in patients with eating disorders.Semantic proximity Read ↗

Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations.Semantic proximity Read ↗

Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type.Semantic proximity Read ↗

Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations.Semantic proximity Read ↗

Food restriction leads to binge eating dependent upon the effect of the brain-derived neurotrophic factor Val66Met polymorphism.Semantic proximity Read ↗

BDNF Val66Met polymorphism, energy intake and BMI: a follow-up study in schoolchildren at risk of eating disorders.Semantic proximity Read ↗

Brain-derived neurotrophic factor, food intake regulation, and obesity.Semantic proximity Read ↗

Association analysis of serotonin receptor 1B (HTR1B) and brain-derived neurotrophic factor gene polymorphisms in Borderline personality disorder.Semantic proximity Read ↗

Genetic susceptibility to eating disorders: associated polymorphisms and pharmacogenetic suggestions.Semantic proximity Read ↗

No association of brain-derived neurotrophic factor Val66Met polymorphism with anorexia nervosa in Japanese.Semantic proximity Read ↗

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