Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations.

doi:10.1038/sj.ejhg.5201351

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Article

Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations.

European journal of human genetics : EJHG - 1 Apr 2005

Ribasés Marta, Gratacòs Mònica, Fernández-Aranda Fernando, Bellodi Laura, Boni Claudette, Anderluh Marija, Cristina Cavallini Maria, Cellini Elena, Di Bella Daniela, Erzegovesi Stefano, Foulon Christine, Gabrovsek Mojca, Gorwood Philip, Hebebrand Johannes, Hinney Anke, Holliday Jo, Hu Xun, Karwautz Andreas, Kipman Amélie, Komel Radovan, Nacmias Benedetta, Remschmidt Helmut, Ricca Valdo, Sorbi Sandro, Tomori Martina, Wagner Gudrun, Treasure Janet, Collier David A, Estivill Xavier

Abstract excerpt

Eating disorders (ED), such as anorexia nervosa (AN) and bulimia nervosa (BN), are complex psychiatric disorders where different genetic and environmental factors are involved. Several lines of evidence support that brain-derived neurotrophic factor (BDNF) plays an essential role in eating behaviour and that alterations on this neurotrophic system participates in the susceptibility to both AN and BN. Accordingly,...

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Identifiers

PMID: 15657604
DOI: 10.1038/sj.ejhg.5201351

Genes

BDNF
NTRK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations.PMID 15657604Read ↗

Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations.Semantic proximity Read ↗

Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type.Semantic proximity Read ↗

Altered brain-derived neurotrophic factor blood levels and gene variability are associated with anorexia and bulimia.Semantic proximity Read ↗

BDNF genetic variability modulates psychopathological symptoms in patients with eating disorders.Semantic proximity Read ↗

Contribution of NTRK2 to the genetic susceptibility to anorexia nervosa, harm avoidance and minimum body mass index.Semantic proximity Read ↗

Brain-derived neurotrophic factor, food intake regulation, and obesity.Semantic proximity Read ↗

Role of the neurotrophin network in eating disorders' subphenotypes: body mass index and age at onset of the disease.Semantic proximity Read ↗

Food restriction leads to binge eating dependent upon the effect of the brain-derived neurotrophic factor Val66Met polymorphism.Semantic proximity Read ↗

The 196G/A (val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorder.Semantic proximity Read ↗

Family trios analysis of common polymorphisms in the obestatin/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: association with subtype, body-mass index, severity and age of onset.Semantic proximity Read ↗

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