Article
Zebrafish orthologs of human muscular dystrophy genes.
BMC genomics - 20 Mar 2007
Steffen Leta S, Guyon Jeffrey R, Vogel Emily D, Beltre Rosanna, Pusack Timothy J, Zhou Yi, Zon Leonard I, Kunkel Louis M
Abstract excerpt
BACKGROUND: Human muscular dystrophies are a heterogeneous group of genetic disorders which cause decreased muscle strength and often result in premature death. There is no known cure for muscular dystrophy, nor have all causative genes been identified. Recent work in the small vertebrate zebrafish Danio rerio suggests that mutation or misregulation of zebrafish dystrophy orthologs can also cause muscular...
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