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Article

Mouse embryo culture induces changes in postnatal phenotype including raised systolic blood pressure.

Proceedings of the National Academy of Sciences of the United States of America - 27 Mar 2007

Watkins Adam J, Platt Duncan, Papenbrock Tom, Wilkins Adrian, Eckert Judith J, Kwong Wing Yee, Osmond Clive, Hanson Mark, Fleming Tom P

Abstract excerpt

A key factor in the use of assisted reproductive technologies (ART) for diverse species is the safety of procedures for long-term health. By using a mouse model, we have investigated the effect of in vitro culture and embryo transfer (ET) of superovulated embryos on postnatal growth and physiological activity compared with that of embryos developing in vivo. Embryo culture from two-cell to blastocyst stages in T6...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17372207
DOI: 10.1073/pnas.0610317104
PMCID: PMC1838459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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