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Article

Grand rounds: could occupational exposure to n-hexane and other solvents precipitate visual failure in leber hereditary optic neuropathy?

Environmental health perspectives - 1 Jan 2007

Carelli Valerio, Franceschini Flavia, Venturi Silvia, Barboni Piero, Savini Giacomo, Barbieri Giuseppe, Pirro Ettore, La Morgia Chiara, Valentino Maria L, Zanardi Francesca, Violante Francesco S, Mattioli Stefano

Abstract excerpt

CONTEXT: Leber hereditary optic neuropathy (LHON) is a maternally inherited loss of central vision related to pathogenic mutations in the mitochondrial genome, which are a necessary but not sufficient condition to develop the disease. Investigation of precipitating environmental/occupational (and additional genetic) factors could be relevant for prevention. CASE PRESENTATION: After a 6-month period of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17366829
DOI: 10.1289/ehp.9245
PMCID: PMC1797843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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