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Article

Rapid sequence evolution of street rabies glycoprotein is related to the highly heterogeneous nature of the viral population.

Virology - 1 Mar 1992

Benmansour A, Brahimi M, Tuffereau C, Coulon P, Lafay F, Flamand A

Abstract excerpt

The sequence of the glycoprotein gene of a street rabies virus was determined directly using fragments of a rabid dog brain after PCR amplification. Compared with that of the prototype strain CVS, this sequence displayed 10% divergence in overall amino acid composition. However only 6% divergence was noted in the ectodomain suggesting that structural constraints are exerted on this portion of the glycoprotein. A...

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PMID: 1736537
DOI: 10.1016/0042-6822(92)90292-w

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