Genetic diversity and molecular evolution of the rabies virus matrix protein gene in China.

doi:10.1016/j.meegid.2013.02.009

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Article

Genetic diversity and molecular evolution of the rabies virus matrix protein gene in China.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2013

Wu Hui, Wang Lihua, Tao Xiaoyan, Li Hao, Rayner Simon, Liang Guodong, Tang Qing

Abstract excerpt

To investigate the diversity of rabies virus (RABV) matrix protein (M) gene in the current Chinese rabies epidemic, we fully examined M gene of 63 street RABVs (Virus isolated from naturally infected animals), and performed phylogenetic and mutational analysis. Our results indicate that the Chinese RABV M gene is well conserved with 90.6% to 100% amino acid similarity. Analysis of the mutations indicates that the...

Topics

Amino Acid Sequence
Animals
Bayes Theorem
China
Evolution, Molecular
Genetic Variation
Molecular Sequence Data
Phylogeny
Rabies
Rabies virus
Sequence Alignment
Viral Matrix Proteins

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Open in PubMed

Identifiers

PMID: 23453987
DOI: 10.1016/j.meegid.2013.02.009

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