Article
Low genetic diversities of rabies virus populations within different hosts in Brazil.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2010
Kobayashi Yuki, Suzuki Yoshiyuki, Itou Takuya, Carvalho Adolorata A B, Cunha Elenice M S, Ito Fumio H, Gojobori Takashi, Sakai Takeo
Abstract excerpt
The low rates of nonsynonymous evolution observed in natural rabies virus (RABV) isolates are suggested to have arisen in association with the structural and functional constraints operating on the virus protein and the infection strategies employed by RABV within infected hosts to avoid strong selection by the immune response. In order to investigate the relationship between the genetic characteristics of RABV...
Topics
- Animals
- Antigens, Viral
- Brain
- Brazil
- Chiroptera
- Databases, Nucleic Acid
- Dogs
- Foxes
- Glycoproteins
- Mutation
- Rabies
- Rabies virus
- Viral Envelope Proteins
