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Factors Maintaining Normal Sperm Tail Structure During Epididymal Maturation Studied in Gopc−/− Mice1

14 Mar 2007

Abstract excerpt

Gopc (Golgi-associated PDZ- and coiled-coil motif-containing protein)(-/-) mice are infertile, showing globozoospermia, coiled tails, and a stratified mitochondrial sheath. Transmission electron microscope (TEM) images of the spermatozoa were studied quantitatively to analyze disorganization processes during epididymal passage. Factors maintaining straight tail and normal mitochondrial sheath were also studied by...

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PMID: 17360959
DOI: 10.1095/biolreprod.106.058735

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