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Article

MAPK interacts with XGef and is required for CPEB activation during meiosis in Xenopus oocytes.

Journal of cell science - 15 Mar 2007

Keady Brian T, Kuo Peiwen, Martínez Susana E, Yuan Lei, Hake Laura E

Abstract excerpt

Meiotic progression in Xenopus oocytes, and all other oocytes investigated, is dependent on polyadenylation-induced translation of stockpiled maternal mRNAs. Early during meiotic resumption, phosphorylation of CPE-binding protein (CPEB) is required for polyadenylation-induced translation of mRNAs encoding cell cycle regulators. Xenopus Gef (XGef), a Rho-family guanine-exchange factor, influences the activating...

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PMID: 17344432
DOI: 10.1242/jcs.03416

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CPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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MAPK interacts with XGef and is required for CPEB activation during meiosis in Xenopus oocytes.PMID 17344432Read ↗

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