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Article

Maternal Acceptance of the Fetus: True Human Tolerance

1 Mar 2007

Abstract excerpt

Induction and maintenance of immunologic tolerance in humans remains a desirable but elusive goal. Therefore, understanding the physiologic mechanisms of regulation of immune responses is highly clinically relevant for immune-mediated diseases (e.g., autoimmunity and asthma/allergy) and for cell and organ transplantation. Acceptance of the fetus, which expresses paternally inherited alloantigens, by the mother...

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PMID: 17339426
DOI: 10.4049/jimmunol.178.6.3345

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