Article
[Genetic markers of predisposition to an aggressive course of chronic C hepatitis].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 2007
Abdullaev S M, Tselishcheva Iu I, Samokhodskaia L M, Kvasovka V V, Ignatova T M, Krasnova T N, Bochkov V N, Mukhin N A
Abstract excerpt
The polymorphism of cytokine genes (11-1beta, IL-10, IL-6, and TGF-beta1) in patients with chronic C hepatitis and in healthy individuals was studied. The study found that the polymorphism of IL-1beta, IL-6, and TGF-beta1 may at least partially explain the genetic predisposition to an aggressive course of the disease with the development of terminal stage.
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