Article
Inheritance, mode of inheritance, and candidate genes for primary hyperparathyroidism in Keeshonden.
Journal of veterinary internal medicine - 1 Jan 2000
Goldstein Richard E, Atwater Daniel Z, Cazolli Dava M, Goldstein Orly, Wade Claire M, Lindblad-Toh Kerstin
Abstract excerpt
BACKGROUND: Primary hyperparathyroidism (PHPT) is caused by inappropriate secretion of parathyroid hormone (PTH) by autonomously functioning neoplastic or hyperplastic parathyroid "chief" cells. Keeshonden are thought to be over-represented in studies on canine PHPT, but no proof of heritability or mode of inheritance has been published. The canine disease clinically resembles human familial isolated...
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