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Article

PKD1 Nonsense Variant in a Lagotto Romagnolo Family with Polycystic Kidney Disease.

Genes - 1 Jun 2023

Drögemüller Michaela, Klein Nadine, Steffensen Rikke Lill, Keiner Miriam, Jagannathan Vidhya, Leeb Tosso

Abstract excerpt

A female Lagotto Romagnolo dog with polycystic kidney disease (PKD) and her progeny, including PKD-affected offspring, were studied. All affected dogs appeared clinically inconspicuous, while sonography revealed the presence of renal cysts. The PKD-affected index female was used for breeding and produced two litters with six affected offspring of both sexes and seven unaffected offspring. The pedigrees suggested...

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Source

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Identifiers

PMID: 37372390
DOI: 10.3390/genes14061210
PMCID: PMC10297835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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