Article
The fate of 12 recessive mutations in a single village.
Annals of human genetics - 1 Mar 2007
Zlotogora J, Hujerat Y, Barges S, Shalev S A, Chakravarti A
Abstract excerpt
In a Muslim Arab village, relatively isolated because of the preference of consanguineous marriages, we studied the fate of 12 mutations in 5 different genes. The study was based on carriers detected among relatives of affected patients and of carriers discovered in a random sample of 424 adults. Most of the mutations have been introduced by a carrier(s) originating from another village, but a few have been de...
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