Article
Impact of aboriginal ethnicity on HCV core-induced IL-10 synthesis: interaction with IL-10 gene polymorphisms.
Hepatology (Baltimore, Md.) - 1 Mar 2007
Aborsangaya Koko Bate, Dembinski Iga, Khatkar Suresh, Alphonse Martin Prince, Nickerson Peter, Rempel Julia D
Abstract excerpt
UNLABELLED: The host immune response is a critical determinant in viral infection outcome. Epidemiological studies indicate that North American indigenous peoples are more resistant to chronic HCV infection than other populations. Due to the prominence of IL-10 in chronic HCV infection, we investigated the genetic tendency to produce IL-10 in Caucasian (CA) and First Nation (FN) populations. Peripheral blood...
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