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Resolution of cervical dysplasia is associated with T-cell proliferative responses to human papillomavirus type 16 E2

26 Feb 2007

Abstract excerpt

The 'high-risk' human papillomaviruses (HPVs) cause persistent infections of the anogenital region that may resolve spontaneously following activation of a protective immune response. The aim of this study was to determine whether cell-mediated immunity (CMI) to the early protein E2 was associated with disease regression and to establish whether E2 CMI and antibodies to L1 virus-like particles (VLPs) were...

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PMID: 17325352
DOI: 10.1099/vir.0.82678-0

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