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Article

Interleukin-1 beta induction of tumor necrosis factor-alpha gene expression in human astroglioma cells.

Journal of neuroimmunology - 1 Feb 1992

Bethea J R, Chung I Y, Sparacio S M, Gillespie G Y, Benveniste E N

Abstract excerpt

Cells that produce tumor necrosis factor-alpha (TNF-alpha) require the presence of signaling molecules since this cytokine is not normally expressed in a constitutive manner. It has been demonstrated that glial cells can produce TNF-alpha; however, the specific inducing molecules and their mechanism(s) of action have not been clearly defined. In this study, we examined the effect of human recombinant...

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Source

Identifiers

PMID: 1732280
DOI: 10.1016/0165-5728(92)90049-q

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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