Article
The rec102 mutant of yeast is defective in meiotic recombination and chromosome synapsis.
Genetics - 1 Jan 1992
Bhargava J, Engebrecht J, Roeder G S
Abstract excerpt
A mutation at the REC102 locus was identified in a screen for yeast mutants that produce inviable spores. rec102 spore lethality is rescued by a spo13 mutation, which causes cells to bypass the meiosis I division. The rec102 mutation completely eliminates meiotically induced gene conversion and crossing over but has no effect on mitotic recombination frequencies. Cytological studies indicate that the rec102...
Topics
- Chromosome Mapping
- Chromosomes, Fungal
- Cloning, Molecular
- Genes, Fungal
- Genetic Complementation Test
- Kinetics
- Meiosis
- Mutation
- Phenotype
- Recombination, Genetic
- Saccharomyces cerevisiae
