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Article

Functional interactions between SPO11 and REC102 during initiation of meiotic recombination in Saccharomyces cerevisiae.

Genetics - 1 Jan 2002

Kee Kehkooi, Keeney Scott

Abstract excerpt

In Saccharomyces cerevisiae, formation of the DNA double-strand breaks (DSBs) that initiate meiotic recombination requires the products of at least 10 genes. Spo11p is thought to be the catalytic subunit of the DNA cleaving activity, but the roles of the other proteins, and the interactions among them, are not well understood. This study demonstrates genetic and physical interactions between the products of SPO11...

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Source

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Identifiers

PMID: 11805049
DOI: 10.1093/genetics/160.1.111
PMCID: PMC1461935

Genes

SPO11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Functional interactions between SPO11 and REC102 during initiation of meiotic recombination in Saccharomyces cerevisiae.PMID 11805049Read ↗

Support for a meiotic recombination initiation complex: interactions among Rec102p, Rec104p, and Spo11p.Semantic proximity Read ↗

The rec102 mutant of yeast is defective in meiotic recombination and chromosome synapsis.Semantic proximity Read ↗

Molecular and genetic analysis of REC103, an early meiotic recombination gene in yeast.Semantic proximity Read ↗

Suppressor analysis of the Saccharomyces cerevisiae gene REC104 reveals a genetic interaction with REC102.Semantic proximity Read ↗

Both conserved and non-conserved regions of Spo11 are essential for meiotic recombination initiation in yeast.Semantic proximity Read ↗

Characterization of REC104, a gene required for early meiotic recombination in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Meiotic association between Spo11 regulated by Rec102, Rec104 and Rec114.Semantic proximity Read ↗

A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae.Semantic proximity Read ↗

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The multiple roles of the Mre11 complex for meiotic recombination.Semantic proximity Read ↗

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