Article
A susceptibility gene set for early onset colorectal cancer that integrates diverse signaling pathways: implication for tumorigenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Feb 2007
Hong Yi, Ho Kok Sun, Eu Kong Weng, Cheah Peh Yean
Abstract excerpt
PURPOSE: The causative genes for autosomal dominantly inherited familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer have been well characterized. There is, however, another 10% to 15% of early onset colorectal cancers (CRC) in which the genetic components are unclear. In this study, we used microarray technology to systematically search for differentially expressed genes in early...
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