Article
Alcohol consumption and distinct molecular pathways to colorectal cancer.
The British journal of nutrition - 1 Mar 2007
Bongaerts Brenda W C, de Goeij Anton F P M, de Vogel Stefan, van den Brandt Piet A, Goldbohm R Alexandra, Weijenberg Matty P
Abstract excerpt
High alcohol consumption is related to colorectal cancer (CRC). Our objective was to study associations between alcohol consumption and risk of CRC according to characteristics of aetiological pathways: the chromosomal instability (CIN) and the microsatellite instability (MIN) pathway. We classified CIN+ tumours (tumours with either a truncating APC mutation, an activating K-ras mutation or overexpression of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
