Article
MLH1 germline epimutations in selected patients with early‐onset non‐polyposis colorectal cancer
12 Jan 2007
Abstract excerpt
Recently, the germline epigenetic inactivation of MLH1 has been reported in a number of patients with early-onset colorectal cancer among other characteristics. The aim of the present study is to evaluate the presence of MLH1 germline epimutations in selected colorectal cancer patients suspected of hereditary non-polyposis colorectal cancer (HNPCC) in order to determine in which patients the MLH1 epigenetic test...
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