Article
Effect of ERCC1 polymorphisms and the modification by smoking on the survival of non-small cell lung cancer patients.
Medical oncology (Northwood, London, England) - 1 Jan 2006
Park So-Yeon, Hong Yun-Chul, Kim Jin-Hee, Kwak Seung-Min, Cho Jae-Hwa, Lee Hong-Lyeol, Ryu Jeong-Seon
Abstract excerpt
A few reports for ERCC1 SNPs were conducted in patients treated with cisplatin chemotherapy. The aim of this study is to determine whether the SNPs are a prognostic factor related to the treatment or not and if smoking level of the patients have any relationship to the SNPs' effect on the survival. Peripheral blood lymphocytes of 423 consecutive non-small cell lung cancer patients were examined: 245 of the...
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