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Article

[Methylation of P15INK4B gene in patients with myelodysplastic syndromes and demethylating effects of drugs].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 Jan 2007

Ye Xue-shi, Liu Ting, Cui Xu, Meng Wen-tong, Xi Ya-ming

Abstract excerpt

OBJECTIVES: To detect the methylation of P15INK4B gene in patients with myelodysplastic syndromes (MDS) and to investigate the demethylating effects of decitabine and arsenic trioxide (As2O3). METHODS: The bone marron mononuclear cells from 14 MDS patients were collected. The methylation of P15INK4B gene was detected with restrictive endonucleases combined with PCR technique. The peripheral blood mononuclear...

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PMID: 17294728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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[Methylation of P15INK4B gene in patients with myelodysplastic syndromes and demethylating effects of drugs].PMID 17294728Read ↗

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Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2′-deoxycytidine (decitabine) treatmentSemantic proximity Read ↗

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Decitabine in the treatment of myelodysplastic syndromesSemantic proximity Read ↗

[A preliminary study on the outcome of lower-risk myelodysplastic syndrome by low-dose decitabine].Semantic proximity Read ↗

Methylation of the <i>p15</i><sup><i>INK4B</i></sup> gene in myelodysplastic syndrome: it can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformationSemantic proximity Read ↗

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