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Article

Cocaine- and amphetamine-regulated transcript (CART) peptide specific binding in pheochromocytoma cells PC12.

European journal of pharmacology - 22 Mar 2007

Maletínská Lenka, Maixnerová Jana, Matysková Resha, Haugvicová Renata, Sloncová Eva, Elbert Tomás, Slaninová Jirina, Zelezná Blanka

Abstract excerpt

CART (cocaine- and amphetamine-regulated transcript) peptides have been studied for ten years. We report specific binding of 125I-CART(61-102) to the rat adrenal pheochromocytoma PC12 cell line, both intact cells and cell membranes. Saturation binding to intact plated cells resulted in Kd of 0.48+/-0.16 nM and Bmax of 2228+/-529 binding sites/cell. 125I-CART(61-102) was also bound to PC12 cells differentiated...

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PMID: 17292884
DOI: 10.1016/j.ejphar.2006.12.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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