Article
Fusogenic variants of a noncytopathic paramyxovirus.
Journal of virology - 1 Apr 2007
Seth Shaguna, Skountzou Ioanna, Gernert Kim M, Compans Richard W
Abstract excerpt
SER virus is a type 5 parainfluenza virus that does not exhibit syncytium formation, in contrast to most other paramyxoviruses. This property has been attributed, at least in part, to the presence of an extension of the cytoplasmic tail (CT) of the SER F protein, as truncations or mutations of this region resulted in enhanced fusion. In this study we used repeated passage to select for mutant SER viruses, which...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
