Article
A simple sandwich ELISA (WELYSSA) for the detection of lyssavirus nucleocapsid in rabies suspected specimens using mouse monoclonal antibodies.
Biologicals : journal of the International Association of Biological Standardization - 1 Oct 2007
Xu Gelin, Weber Patrick, Hu Qiaoling, Xue Honggang, Audry Laurent, Li Chengping, Wu Jie, Bourhy Herve
Abstract excerpt
Monoclonal antibody (MAb)-based capture enzyme-linked immunosorbent assays (ELISA) were developed for the diagnosis of rabies-suspect specimens. A combination of four mouse monoclonal antibodies directed against the rabies virus nucleocapsid was selected and used for the detection. The test was optimized and standardized so that maximum concordance could be maintained with the standard procedures of rabies...
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