Article
Anomalies of the TCF2 gene are the main cause of fetal bilateral hyperechogenic kidneys.
Journal of the American Society of Nephrology : JASN - 1 Mar 2007
Decramer Stéphane, Parant Olivier, Beaufils Sandrine, Clauin Séverine, Guillou Cécile, Kessler Sylvie, Aziza Jacqueline, Bandin Flavio, Schanstra Joost P, Bellanné-Chantelot Christine
Abstract excerpt
Prenatal discovery of fetal bilateral hyperechogenic kidneys is very stressful for pregnant women and their family, and accurate diagnosis of the cause of the moderate forms of this pathology is very difficult. Hepatocyte nuclear factor-1beta that is encoded by the TCF2 gene is involved in the embryonic development of the kidneys. Sixty-two pregnancies with fetal bilateral hyperechogenic kidneys including 25...
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