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Article

Renal phenotypes related to hepatocyte nuclear factor-1beta (TCF2) mutations in a pediatric cohort.

Journal of the American Society of Nephrology : JASN - 1 Feb 2006

Ulinski Tim, Lescure Sandra, Beaufils Sandrine, Guigonis Vincent, Decramer Stéphane, Morin Denis, Clauin Séverine, Deschênes Georges, Bouissou François, Bensman Albert, Bellanné-Chantelot Christine

Abstract excerpt

The hepatocyte nuclear factor-1beta encoded by the TCF2 gene plays a role for the specific regulation of gene expression in various tissues such as liver, kidney, intestine, and pancreatic islets and is involved in the embryonic development of these organs. TCF2 mutations are known to be responsible for the maturity-onset diabetes of the young type 5 associated with renal manifestations. Several observations have...

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PMID: 16371430
DOI: 10.1681/ASN.2005101040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Renal phenotypes related to hepatocyte nuclear factor-1beta (TCF2) mutations in a pediatric cohort.PMID 16371430Read ↗

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