Article
RpoS as an intermediate in RsmA-dependent regulation of secondary antifungal metabolites biosynthesis in Pseudomonas sp. M18.
FEMS microbiology letters - 1 Mar 2007
Ge Yihe, Yang Shude, Fang Yanyu, Yang Runya, Mou Daiying, Cui Jinpeng, Wen Lu
Abstract excerpt
To investigate the regulatory mechanism governing antifungal metabolite biosynthesis, two kinds of global regulator genes in Pseudomonas sp. M18, an rpoS and an rsmA gene, were cloned and mutated by inserting with an aacC1 cassette, respectively. Two mutants showed the same regulatory mode with repression of phenazine-1-carboxylic acid and remarkable enhancement of pyoluteorin. In the rpoS-mutant, a translational...
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