Article
The predicted transmembrane fragment 17 of the human multidrug resistance protein 1 (MRP1) behaves as an interfacial helix in membrane mimics.
Biochimica et biophysica acta - 1 Mar 2007
Vincent Michel, Gallay Jacques, Jamin Nadège, Garrigos Manuel, de Foresta Béatrice
Abstract excerpt
The human multidrug resistance protein MRP1 (or ABCC1) is one of the most important members of the large ABC transporter family, in terms of both its biological (tissue defense) and pharmacological functions. Many studies have investigated the function of MRP1, but structural data remain scarce f...
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