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Article

Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells

26 Jan 2007

Abstract excerpt

INTRODUCTION: Cancer is a leading cause of death in Americans. We have identified an inducible cancer avoidance mechanism in cells that reduces mutation rate, reduces and delays carcinogenesis after carcinogen exposure, and induces apoptosis and/or senescence of already transformed cells by simultaneously activating multiple overlapping and redundant DNA damage response pathways. METHODS: The human breast...

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PMID: 17257427
DOI: 10.1186/bcr1646

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