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Article

Repressive Effect of Sp1 on the C/EBPα Gene Promoter: Role in Adipocyte Differentiation

1 Jul 1999

Abstract excerpt

Expression of C/EBPalpha is required for differentiation of 3T3-L1 preadipocytes into adipocytes. Previous investigations indicated that transcription of the C/EBPalpha gene is sequentially activated during differentiation, initially by C/EBPbeta and C/EBPdelta and later by C/EBPalpha (autoactivation). These events are mediated by a C/EBP regulatory element in the promoter of the C/EBPalpha gene. This article...

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Identifiers

PMID: 10373535
DOI: 10.1128/mcb.19.7.4855

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